Ensure you are running the latest stable version of Apache HTTPD. Most exploits target unpatched vulnerabilities in older software.
On January 31, 2012, the Apache Software Foundation released version 2.2.22 apache httpd 2222 exploit
Apache 2.2.22 is a legacy version (released in 2012) and is subject to several known vulnerabilities. Modern vulnerability scanners often flag this version because it lacks the cumulative security patches found in later 2.2.x or 2.4.x releases. CVE-2012-0053 (Critical): A vulnerability in the way Ensure you are running the latest stable version
If you want, I can: