These programs exist solely for nonlinear modeling. They offer granular control over algorithms.
While Phoenix WinNonlin is the dominant player, the landscape is diversifying. Open-source languages like (with packages like nls ) and Python are increasingly used for custom modeling. Additionally, NONMEM remains the gold standard for "Population PK," which looks at how drug effects vary across a diverse population.
Beyond physical structures, nonlinear software is used to solve complex mathematical puzzles. Minitab Statistical Software's Nonlinear Regression Tool 22 Nov 2017 —
